Inference of Joint Conformational Distributions from Separately Acquired Experimental Measurements
نویسندگان
چکیده
منابع مشابه
Unicast inference of network link delay distributions from edge measurements
Inference of network internal link characteristics has become an increasingly important issue for operating and evaluating large telecommunication networks. Since it is usually impractical to directly monitor each link along a specific path, end-to-end probes are sometimes used to collect link characteristic information at edge nodes of the network. This paper deals with unicast probing methods...
متن کاملExperimental joint quantum measurements with minimum uncertainty.
Quantum physics constrains the accuracy of joint measurements of incompatible observables. Here we test tight measurement-uncertainty relations using single photons. We implement two independent, idealized uncertainty-estimation methods, the three-state method and the weak-measurement method, and adapt them to realistic experimental conditions. Exceptional quantum state fidelities of up to 0.99...
متن کاملIdentifiability of flow distributions from link measurements
We study the problem of identifiability of distributions of flows on a graph from aggregate measurements collected on its edges. This is a canonical example of a statistical inverse problem motivated by recent developments in computer networks. In this paper (i) we introduce a number of models for multi-modal data that capture their spatio-temporal correlation, (ii) provide sufficient condition...
متن کاملJoint Causal Inference on Observational and Experimental Datasets
We introduce Joint Causal Inference (JCI), a powerful formulation of causal discovery from multiple datasets that allows to jointly learn both the causal structure and targets of interventions from statistical independences in pooled data. Compared with existing constraint-based approaches for causal discovery from multiple data sets, JCI offers several advantages: it allows for several differe...
متن کاملConformational distributions of unfolded polypeptides from novel NMR techniques.
How the information content of an unfolded polypeptide sequence directs a protein towards a well-formed three-dimensional structure during protein folding remains one of the fundamental questions in structural biology. Unfolded proteins have recently attracted further interest due to their surprising prevalence in the cellular milieu, where they fulfill not only central regulatory functions, bu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physical Chemistry Letters
سال: 2021
ISSN: 1948-7185,1948-7185
DOI: 10.1021/acs.jpclett.0c03623